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Cheap Flights from Madrid to Panama City starting at S$ 406

Book one-way or return flights from Madrid to Panama City from as little as S$ 406. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cheapest time to fly from Madrid to Panama City

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.
Cheapest Airlines flying from Madrid to Panama City

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca
From S$ 405
Air Europa
From S$ 447
Wizz Air Malta
From S$ 468
ITA Airways
From S$ 545
Plus Ultra Lineas Aereas, S. A.
From S$ 636
Vueling Airlines
From S$ 637
easyJet
From S$ 648
Royal Air Maroc
From S$ 678
IBERIA
From S$ 717
LATAM Airlines
From S$ 734
ANA airlines

Find more flights and airlines

Alternative Routes from Madrid to Panama City

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Madrid to Panama City.

  • Cheapest
    Avianca
    MAD
    09:40
    18h 5m
    1 transfer
    PTY
    20:45
    Madrid Barajas Airport - Tocumen International Airport
    Thu, Apr 11Avianca
    S$ 406
  • Avianca
    MAD
    09:40
    18h 5m
    1 transfer
    PTY
    20:45
    Madrid Barajas Airport - Tocumen International Airport
    Thu, Apr 11Avianca
    S$ 406
    Find More Flights

Frequently Asked Questions

  • When to buy flight tickets from Madrid (MAD) to Panama City (PTY) the cheapest?

    Airlines adjust prices for flights from Madrid to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much is a flight from Madrid (MAD) to Panama City (PTY) cost?

    According to Trip.com's data, the lowest price is around S$ 1,392.
  • How long is a flight from Madrid (MAD) to Panama City (PTY)?

    It takes about 10 hours 42 minutes to fly from Madrid (MAD) to Panama City (PTY).
  • What is the transportation method from the main airport to downtown in Panama City?

    • The distance from Tocumen International Airport to downtown is about 16km, by taxi about 30 minutes.
    • The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5km, by taxi about 20 minutes.
  • What are the most popular airlines that fly from Madrid (MAD) to Panama City (PTY)?

    Airlines with flights from Madrid (MAD) to Panama City (PTY): Air Europa, IBERIA, Copa Airlines, Qatar Airways, British Airways and El Al.
  • What's the most popular airline for direct flights from Madrid (MAD) to Panama City (PTY)?

    IBERIA operates 2 direct flights from Madrid (MAD) to Panama City (PTY).
  • How many airports in Panama City?

Find cheapest flight ticket from Madrid to Panama City

Cheapest direct flight price

S$ 405

Cheapest return ticket price

S$ 823

Cheapest month

March

Peak season for travel

October